The Single Best Strategy To Use For modafinil norge
The Single Best Strategy To Use For modafinil norge
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Stiripentol is usually a CYP3A4 inhibitor and inducer. Observe CYP3A4 substrates coadministered with stiripentol for increased or diminished results. CYP3A4 substrates may perhaps demand dosage adjustment.
Modafinil appeared to create a focus-connected suppression of CYP2C9 action, thus suggesting potential for CYP2C9 inhibition; warning if prescription drugs that have a narrow therapeutic index
A Unique MedGuide will be offered to you personally because of the pharmacist with Each and every prescription and refill. You'll want to read this information cautiously every time.
In the same way, it is actually at this time mysterious irrespective of whether modafinil might be transmitted to an toddler by means of breastmilk, and similar cautions utilize to modafinil use by moms who are nursing [38].
Keep track of Closely (one)mitotane decreases amounts of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Mitotane is a robust inducer of cytochrome P-4503A4; check when coadministered with CYP3A4 substrates for feasible dosage adjustments.
Watch Closely (one)voriconazole will increase the level or effect of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
modafinil will lower the level or outcome of pacritinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
modafinil will lessen the extent or impact of levoketoconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
Prescription drugs that have limits other than prior authorization, amount limitations, and move therapy related to each prescription.
rifampin will decrease the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
modafinil will raise the stage or effect of diazepam buccal by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Robust or moderate CYP2C19 inhibitors could lessen amount of diazepam elimination, thus increasing adverse reactions to diazepam.
Warfarin's fewer potent R-enantiomer is metabolized in part by CYP3A4 (and in addition CYP1A2 and CYP2C19). Keep an eye on INR far more usually if coadministered with inhibitors of these isoenzymes and regulate warfarin dose if needed.
The current analyze utilized meta-Evaluation to combine the offered literature within the therapy of modafinil on tiredness and EDS affiliated with neurological Issues and assessed the efficacy of modafinil on exhaustion and EDS and its security in people with neurological conditions with a rigorous methodological good quality evaluation.
Prescription drugs which have amount limits affiliated with Every single prescription. This restriction typically website limitations the quantity of your drug that may be coated.